The discovery and development of this first sulfonamide drug opened a new era in medicine. It was developed in the 1930s by a research team at the Bayer Laboratories of the IG Farben conglomerate in Germany. Prontosil was the first commercially available antibacterial antibiotic (with a relatively broad effect against Gram-positive cocci.
This is a fascinating scientific tale with all the excitement and intrigue of a great suspense novel.The Demon Under the Microscope: From Battlefield Hospitals to Nazi Labs, One Doctor's Heroic Search for the World's First Miracle Drug is a 2006 nonfiction book about the discovery of Prontosil, the first commercially available antibacterial antibiotic and sulfanilamide, the second commercial antibiotic. The very concept that chemicals created in a lab could cure disease revolutionized medicine, taking it from the treatment of symptoms and discomfort to the eradication of the root cause of illness.Ī strange and colorful story, The Demon Under the Microscope illuminates the vivid characters, corporate strategy, individual idealism, careful planning, lucky breaks, cynicism, heroism, greed, hard work, and the central (though mistaken) idea that brought sulfa to the world. Sulfa changed the way new drugs were developed, approved, and sold transformed the way doctors treated patients and ushered in the era of modern medicine.
Sulfa saved millions of lives-among them those of Winston Churchill and Franklin Delano Roosevelt Jr.-but its real effects are even more far reaching. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of sulfa, the first antibiotic and the drug that shaped modern medicine.
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